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Clean Room Maintenance

November 26, 2021



In order to ensure the normal operation of the clean room, we must strictly implement the relevant regulations when operation and pay attention to daily and regular maintenance. So, what aspects should the daily maintenance of the clean room start from? How should the clean room be maintained regularly?



Ⅰ. Regular Maintenance of Clean Room


1. Daily Maintenance


1.1 The cleaning and disinfection of the inside includes color steel plate surface, glass surface, floor and floor drain.

1.2 The cleaning and wiping of indoor equipment, pipes, lamps, etc.

1.3 Scrubbing and disinfection of air shower.

1.4 The cleaning of the outside includes the color steel plate surface, glass surface, floor, sterilization cabinet, disinfection sink, conveyor belt entrance and exit.


2. Monthly Maintenance


2.1 Cleaning and sanitation of the clean room ceiling. If cracks, corrosion or coating on the ceiling and walls are found, sealant must be added and decontamination treatment must be carried.

2.2 The cleaning and sanitation work in the return air duct includes the cleaning of the glass surface, of the color steel plate surface and of the ground.

2.3 Clean and scrub the air conditioner once a month.

2.4 Check the rotation of the fan and air valve, the lubrication of the rotating parts, the bearing and the bearing seat, and add lubricating oil regularly to ensure flexible rotation.


3. Yearly Maintenance


3.1 When the equipment is not at working period, the heat exchanger should be filled with water (close the outlet valve first, then the inlet valve) to reduce pipe rust, but in cold and icy areas in winter, the remaining water should be drained to avoid freezing and cracking of the copper pipe (especially the clean air-conditioning box).

3.2 After two years of operation, chemical methods should be used to remove the scale in the copper pipe of the heat exchanger, and the dirt on the surface of the heat exchanger should be flushed with compressed air or water until it is clean.

3.3 Check whether there is rust and paint peeling inside the air-conditioning box, water tank, and air duct, remove and repair the paint in time; check whether the air control valve of each part is damaged and repair it in time; check the electrical control box, switchboard, and electrical connection to make sure there is no loosening and over-heating, check whether the operation of the meter is normal, etc., and repair them in time; regularly inspect, calibrate the measurement and control the meter and equipment to ensure that its control is accurate and reliable.

3.4 Adjust the tightness of the belt, see the tightness of the fan drive belt or stop the hand pressure over 10mm or tighten it to less than 10mm. Damaged belts should be replaced and equipped in time.

3.5 Under normal circumstances, the HEPA filter is generally replaced once every 5 years at the longest without damage or over-resistance. The bag filter and pre filter can be replaced according to the product and the cleaning quality. The replacement period of the pre filter can be different. Replace directly when the pressure difference is doubled.

If the following conditions are found, HEPA filter should be replaced:

● Air flow speed drops to the limit, even after the pre filter and medium filter are replaced, the air flow speed cannot be increased;

● Resistance of HEPA filter reaches 1.5-2 times of the initial resistance, and the air flow of HEPA filter is 70% of the original air flow;

● HEPA filter is damaged and leaks that cannot be repaired.

3.6 UV lamp generally have a service life of 3000h, but they need to be replaced when the efficiency drops to 70%; the replacement and maintenance, should be registered and recorded for future reference and management.


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Ⅱ. Other Regular Maintenance of Clean Room


1. Number of dust particles

Use a dust particle counter to measure the number of dust particles above 0.5μm and above 5μm in the clean room at regular intervals.

2. Number of colonies

Use a microbiological analyzer to determine the number of colonies such as settling bacteria and planktonic bacteria at regular intervals.

3. Air flow

Measure the pressure difference of the HEPA filter used in air conditioners, and check the leak detection caused by the clogging of air filter, the gap of the installation part, or the damaged surface of air filter. Check the air flow of the air supply and air return with an anemometer twice a year.


KLC has nearly 20 years of experience in the purification industry. Since its establishment, it has been committed to product development and development in the field of air cleaning, and has been constantly improving its products and services with ample enthusiasm. KLC products provide advanced, high-quality, reasonable and economical products and perfect technical services for various fields and industries around the world, allowing you to experience safety, reliability and confidence in the cooperation with KLC.


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